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Subclinical hypothyroidism and pregnancy

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Regarding subclinical hypothyroidism in pregnancy:

  • the serum TSH levels are increased above the upper limit of reference range and the free T4 values are normal (1)
  • there is evidence that this condition is associated with increased risk of having a baby complicated by placental abruption, preterm birth, admission to the neonatal intensive care nursery, and respiratory distress (2)
  • given its potential to reduce the miscarriage rate, T4 supplementation is recommended for infertile women with subclinical hypothyroidism and/or thyroid autoimmunity who are undergoing IVF/ICSI (3)
  • seek specialist advice re: management

Reference:


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