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Frequency of creatinine/eGFR testing

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Kidney function should be measured at least annually in the risk groups below:

Previously diagnosed CKD, including

  • polycystic kidney disease
  • reflux nephropathy
  • biopsy-proven chronic glomerulonephritis
  • persistent proteinuria
  • urologically unexplained persistent haematuria

Conditions associated with a high risk of obstructive nephropathy, including

  • known or suspected bladder outflow obstruction
  • neurogenic bladder caused by spina bifida or spinal cord injury (N.B. calculated GFR may overestimate true GFR in these patients because of decreased muscle mass)
  • urinary diversion surgery
  • urinary stone disease due to primary hyperoxaluria, cystinuria, Dent?s disease, infections (with struvite stones), anatomical abnormalities, or a stone episode rate of > 1/y Conditions known to be associated with a high risk of silent development of CKD, including
  • hypertension
  • diabetes mellitus
  • heart failure
  • atherosclerotic coronary, cerebral, or peripheral vascular disease

Conditions requiring long-term treatment with potentially nephrotoxic drugs, including

  • ACEIs and ARBs
  • NSAIDs
  • lithium carbonate
  • mesalazine and other 5-aminosalicylic acid drugs
  • calcineurin inhibitors (Cyclosporin, Tacrolimus)

Multisystem diseases that may involve the kidney, including systemic lupus erythematosus (SLE), vasculitis, myeloma, rheumatoid arthritis

A first degree relative with stage 5 CKD

Minimum frequency of measurement of kidney function according to estimated GFR (2) :

How frequently do you need to measure eGFR?

Stage

eGFR range (ml/min/1.73 m^22)

Typical frequency of testing

1 and 2

> 60 + other evidence of kidney disease

12 monthly

3A and 3B

30-59

6 monthly

4

15-29

3 monthly

5

<15

6 weekly

Reference:

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