morphine to diamorphine equivalence in chronic usage

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1mg SC diamorphine = 3mg oral morphine = 1.5mg SC morphine

Diamorphine was traditionally used as the first line injectable strong opioid as it is more water soluble than morphine. Morphine sulphate injection is now used in many centres as the first line injectable strong opioid.

Diamorphine preparations: Injection: 5mg, 10mg, 30mg, 100mg, 500mg in packs of 5 ampoules.


  • 1) West Midlands Palliative Care Physicians (2012). Palliative care - guidelines for the use of drugs in symptoms control.

Last reviewed 02/2019