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Polymyalgia rheumatica (PMR) relapse

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

relapse of polymyalgia rheumatica

Relapse is the recurrence of symptoms of PMR or onset of GCA, and not just unexplained raised ESR or CRP

Treatment of relapse:

  • if clinical features of GCA - treat as GCA (usually oral prednisolone 40-60mg daily) (see GCA guideline)

  • if clinical features of PMR - increase prednisolone to previous higher dose

    • single IM. injection of methylprednisolone (depomedrone) 120mg can also be used.
    • further relapses: consider introducing DMARD therapy after two relapses (1)

Reference:

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