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Non-alcoholic fatty liver disease (NAFLD) risk factors

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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risk factors associated with non alcoholic fatty liver disease

Conditions with established association

  • obesity
    • is a common and well documented risk factor for NAFLD and is the main cause for the greater prevalence of NAFLD in the community
  • type 2 diabetes mellitus
    • association between NAFLD and type 2 diabetes is greater (even beyond adiposity)
    • male sex and a family history of type 2 diabetes are also linked with a greater risk of NAFLD and NASH at any given body mass index
  • dyslipidemia
  • metabolic syndrome

Conditions with emerging association

  • polycystic ovary syndrome
  • hypothyroidism
  • obstructive sleep apnoea
  • hypopituitarism
  • hypogonadism
  • pancreato-duodenal resection

Reference:

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