overflow proteinuria

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Overflow proteinuria is associated with disorders which cause an excess of low molecular mass proteins in the plasma:

    • amylase in acute pancreatitis
    • Bence-Jones protein in multiple myeloma
    • Waldenstrom's macroglobulinaemia
    • light chain disease
    • haemoglobin in intravascular haemolysis
    • myoglobin following crush injury
    • lysozyme in myelomonocytic leukaemia / M4 acute myeloid leukaemia

Last reviewed 08/2021