Trousseau's sign of visceral malignancy

Last reviewed 03/2022

This is a recurring thrombophlebitis characterised by successive crops of tender nodules in affected blood vessels. Different veins may be affected simultaneously or randomly. It denotes a thrombotic state and is associated with visceral malignancy, especially of the pancreas and lung. The basis is unknown.

Thrombophlebitis migrans was first recognised by Trousseau in the diagnosis of his own pancreatic cancer.