Transposition of the great arteries

Transposition of the great arteries is diagnosed when the the aorta is connected to the anatomic right ventricle and the pulmonary artery is connected to the anatomic left ventricle.

In TGA the pulmonary and systemic circulations function in parallel rather than in series. The neonate will only survive if there is mixing of the two circulations, ie persistence of the ductus arteriosus and/or the foramen ovale.

• accounts for 3% of all congenital heart disease and 20 % of cyanotic heart disease (1)
• incidence is estimated at is 4.7 per 10,000 live births (1)

Reference:

• Szymanski MW, Moore SM, Kritzmire SM, et al. Transposition Of The Great Arteries. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538434/