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Pre-scleroderma

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Pre-scleroderma is a mild form of systemic sclerosis; it is characterised by:

  • Raynaud's phenomenon
  • nailfold telangiectasiae
  • digital ischaemia

Immunological investigation may reveal the following autoantibodies:

  • anti-Scl-70
  • anti-centromere (ACA)
  • nucleolar

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