danthron containing laxatives
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- danthron is a stimulant laxative
- it is marketed as co-danthrusate (when combined with docusate) and co-danthramer (when combined with poloxamer '188')
- danthron is genotoxic and has been shown to be carcinogenic in rodent studies
- the Committee on Safety on Medicines (CSM) has advised that the use of danthron-containing products be restricted to constipation in the terminally ill patients of all ages
Reference:
- Current Problems in Pharmacovigilance (2000), 26, 4.
Last reviewed 11/2019
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