This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Pancreolauryl test

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

This is a non-invasive test of pancreatic exocrine function. It depends on the hydrolysis of fluorescein dilaurate by cholesterol ester hydrolase, an enzyme normally present in pancreatic juice. Fluorescein is water soluble. It is absorbed by the intestine, conjugated in the liver, and excreted in the urine where it's fluorescence can be measured.

On day one, a tablet containing fluorescein dilaurate is taken and urine collected for 10 hours. On day two, the same procedure is repeated but this time using a tablet containing the equivalent dose of free fluorescein. This allows for correction in individual variations in intestinal, hepatic and renal function.

Results are expressed as the ratio of fluorescein excreted after fluorescein dilaurate and after free fluorescein. A ratio of less than 20% is considered abnormal.


Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.