Last reviewed 01/2018

Trypsin is an enzyme secreted by acinar cells of the pancreas in its inactive form trypsinogen. The inactive form is converted to the active form by the action of an enzyme on the small intestinal brush border, enteropeptidase.

Trypsin digests polypeptide chains into shorter chains, tripeptides and dipeptides.

Trypsin can split pancreatic chymotrypsinogen into chymotrypsin.