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Physiological responses

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

There are two key physiological mechanisms for increasing heat loss from the body of Man:

  • sweating
  • vasodilatation

Generally, both act in tandem to lower core temperature under the integration of the hypothalamus. However, there may be situations when either mechanism is inefficient or disordered e.g. high external humidity or anticholinergic drugs for sweating, and the use of alpha-adrenoceptor blocking drugs for vasodilatation.

Decreased heat production is a theoretical means of decreasing temperature. In practice, the metabolic rate is unchanged; the only contribution to decreasing temperature is an inhibition of shivering and non-shivering thermogenesis. This is not as important as sweating and vasodilatation.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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