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Authoring team

Infective endocarditis frequently presents with vague early symptoms which delays diagnosis. The clinician should be alerted to the possibility of the disease if there are any of the following:

  • known cardiac disease
  • unexplained febrile illness
  • unexplained cardiac failure
  • unexplained embolic events
  • unexplained neurologic illness, especially if febrile
  • unexplained raised ESR or anaemia
  • septicaemia
  • recent surgical or invasive procedures
  • haemodialysis
  • central IV lines
  • IV drug abuse

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