lipid lowering drugs
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There are classified as:
- exchange resins } for most patients replaced
- nicotinic acid and analogues} by statins as first line agents
- fibrates - effective at lowering triglyceride levels and increasing HDL-cholesterol, in addition to lowering LDL-cholesterol - generally also used as a second line treatment to statins
- HMG CoA reductase inhibitors (statins) - the most potent drugs for treating hypercholesterolaemia
- others
- e.g. fish-oil preparations rich in omega-3 marine triglycerides - useful in the treatment of severe hypertriglyceridaemia; however may sometimes aggravate hypercholesterolaemia
- e.g. agents such as ezetimibe, the first selective cholesterol absorption inhibitor, have been introduced then this means there are further options in the management of hyperlipidaemia
Last reviewed 06/2021
Links:
- exchange resins
- fibrates
- HMG CoA reductase inhibitors
- nicotinic acid analogues
- ispaghula as a lipid-lowering drug
- fish oils as a lipid lowering drug
- trials with respect to treatment of hypercholesterolaemia
- ezetimibe
- lipid lowering treatment in primary prevention
- lipid lowering treatment for secondary prevention
- red rice as a lipid lowering treatment
- proprotein convertase subtilisin/kexin type 9 serine protease (PCSK9) inhibitors
- bempedoic acid