raised i/c pressure in palliative care

Last edited 08/2020 and last reviewed 08/2020

Seek Expert advice.

The main symptoms are nausea, vomiting and headache. Avoid lying the patient flat which exacerbates the pressure.

  • Cyclizine - first line for nausea and vomiting due to raised intracranial pressure: stat dose 50mg oral/s.c. total dose 100-150mg oral/s.c. over 24 hours

  • Dexamethasone may be added to reduce symptoms due to brain oedema - dose 6-16 mg per day

  • for possible alternative treatments, seek advice

Radiotherapy of the head or neck may cause similar symptoms.


  1. West Midlands Palliative Care Physicians (2012). Palliative care - guidelines for the use of drugs in symptom control.