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Exchange transfusion

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Exchange transfusion will give an urgent reduction in the serum levels of bilirubin, especially where the hyperbilirubinaemia is the result of rhesus isoimmunisation.

For treatment threshold graphs for phototherapy and exchange transfusion for babies with gestational ages from 23 weeks to 38 weeks or more

Consensus-based bilirubin thresholds for management of babies 38 weeks or more gestational age with hyperbilirubinaemia

Table: An exchange transfusion should be performed unless the bilirubin level falls below threshold while the treatment is being prepared

Age (hours)

Bilirubin measurement (micromol/litre)

0

> 100

6

> 150

12

> 200

18

> 250

24

> 300

30

> 350

36

> 400

42

> 450

48

> 450

54

> 450

60

> 450

66

> 450

72

> 450

78

> 450

84

> 450

90

> 450

96+

> 450

 

Reference:


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