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Diamorphine hydrochloride

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Diamorphine hydrochloride is a morphine derivative, with antitussive and analgesic properties used in the relief of cough and pain in terminal disease. It is contraindicated in other situations because of its addictive properties, and its tendency to cause sputum retention and ventilatory failure.

It is more potent than morphine, causes less nausea and hypotension, and its greater solubility allows effective doses to be given in smaller injected volumes - this property is useful in the emaciated patient.

Its capacity to produce euphoria gives it great potential for causing dependence. Tolerance develops: an increased dose is needed to produce pleasurable effects. It is usually bought in a brownish powder, and is smoked - "chasing the dragon" - or dissolved in acid for injection.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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