This site is intended for healthcare professionals

CPD
CPD
Pro
Pro
account_circleSign in
Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Diagnosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • Hamm's test or acid-haemolysis test

  • sucrose haemolysis test or sugar water test:
    • a medium of low ionic strength, e.g. isotonic sucrose is used to aggregate serum globulins onto the surface of red cells
    • this activates complement which then lyses PNH red cells
    • the sucrose haemolysis test is more sensitive but less specific than the Ham test and best used as a screen

  • immunophenotype analysis for deficient antigen expression:
    • CD59 for red cells and platelets
    • CD67 for granulocytes
    • CD14 for monocytes
    • CD24 for B cells

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.