CRP shows an earlier (begins 4-6 hrs), more intense rise than ESR, in any acute inflammatory change. With recovery, disappearance of CRP precedes the return to normal of ESR. If the inflammatory process is suppressed by steroids or salicylates, then the CRP rise disappears.
Possible conditions that may cause a rise in CRP include:
Active, severe SLE produces almost no increase in CRP unless there is concurrent infection.
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