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Cimetidine

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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This is a H2-receptor antagonist that is used in the treatment of peptic ulceration, oesophagitis and Zollinger- Ellison syndrome.

Some side effects of cimetidine:

  • Cimetidine blocks hepatic cytochrome P-450 and thus slows the metabolism of certain drugs e.g. phenytoin, warfarin, aminophylline.
  • blocks androgen receptors - results in gynaecomastia
  • causes reversible mental confusion (a rare side effect)
  • associated with agranulocytosis (this side effect is also associated with ranitidine)

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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