This site is intended for healthcare professionals

CPD
CPD
Pro
Pro
account_circleSign in
Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The clinical features of Behcet's disease comprise (1,2):

  • arthritis: occurs in 45% of cases, frequently the presenting feature long before other clinical manifestations (2)
    • polyarthritis
    • polyarthralgia of large joints – knees and ankles most involved
  • mucocutaneous:
    • painful oral, vulval, vaginal, penile and scrotal ulcers which heal by scarring
    • erythema nodosum
    • pseudofolliculitis, papulopustular lesions
    • acneiform nodules
  • ocular:
    • iridocyclitis
    • chronic, relapsing bilateral non-granulomatous uveitis
      • may involve anterior, posterior or both (panuveitis)
    • hypopyon
    • optic atrophy
    • cataract
    • glaucoma
    • retinal detachment
  • neurologic:
    • multiple sclerosis and parkinsonism-like disorders
    • dementia
    • meningoencephalitis and brainstem problems
    • Neurobehcet’s disease – parenchymal lesion (2)
  • others:
    • venous thrombosis
    • thrombophlebitis
    • abdominal pain – ileocecal region is most commonly affected
    • nausea, anorexia and diarrhoea
    • haemoptysis

Reference:

  1. Nair JR, Moots RJ. Behcet’s disease. Clin Med (Lond). 2017 Feb;17(1):71-77. Doi: 10.7861/clinmedicine.17-1-71. PMID: 28148585; PMCID: PMC6297594.
  2. Greco A, De Virgilio A, Ralli M, Ciofalo A, Mancini P, Attanasio G, de Vincentiis M, Lambiase A. Behçet's disease: New insights into pathophysiology, clinical features and treatment options. Autoimmun Rev. 2018 Jun;17(6):567-575.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.