Last reviewed 01/2018
Behcet's syndrome is a systemic venulitis.
The aetiology of Behcet's disease is not fully understood, however, the following is known:
- there is a strong HLA association with HLA-B51
- HLA-B51, B12, DR2 and DR7 may influence the organs involved in the disease process
- studies have indicated that herpes simplex virus may be of aetiological significance
There is also evidence of an association between Behcet's disease and HLA-B5 (1).