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Extrapyrimidal effects and atypical antipsychotic drugs

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • extrapyramidal effects rarely occur with clozapine
  • also, in placebo-controlled trials, the incidence of such effects was not increased by quetiapine across its full dose range
  • with amisulpride, olanzapine and risperidone, extrapyramidal effects can occur at the upper end of the licensed dose range - however, the incidence is generally low at the doses most patients receive
  • extrapyramidal effects appear to be uncommon with aripiprazole and zotepine

Reference:

  1. Drug and Therapeutics Bulletin (2004); 42(8):57-60.

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