This lesion is almost always (99%) due to rheumatic heart disease although a clear history is obtained in only 50% of cases.
25% of patients with rheumatic heart disease have pure mitral stenosis, two-thirds are female.
In parallel with the incidence of rheumatic fever, mitral stenosis is more common and generally more severe in developing countries.
NICE state (1):
* severity of valve disease is defined in line with the British Society of Echocardiography guidelines on the British Heart Foundation's website.
Reference:
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