Infection with Epstein-Barr virus (EBV) produces jaundice in 10-15% of cases. Hepatomegaly may be accompanied by pharyngitis, lymphadenopathy and splenomegaly.
Diagnosis is confirmed by atypical blood lymphocytes and a positive monospot test. Note that a monospot test may be falsely positive in hepatitis A infection.
Chronic liver disease does not occur.
Last reviewed 01/2018