aetiology of nephrotic syndrome in adults

Last reviewed 01/2018

A study of 500 cases of nephrotic syndrome in adults presenting to a London teaching hospital between 1963 and 1970 produced the following frequencies for the different aetiologies:

Aetology Frequency (%)
minimal change glomerulonephritis 22.0
membranous glomerulonephritis 19.7
other proliferative glomerulonephritis 16.0
focal segmental glomerulosclerosis 11.8
systemic lupus erythematosus 10.8
membranoproliferative glomerulonephritis 9.8
amyloidosis 5.9
diabetes mellitus 1.6