aetiology of nephrotic syndrome in children

Last reviewed 01/2018

A study of 200 cases of nephrotic syndrome in children presenting to a London teaching hospital between 1963 and 1970 produced the following frequencies for the different aetiologies:

Aetiology Frequency (%)
minimal change glomerulonephritis 76.0
focal segmental glomerulosclerosis 7.0
membranoproliferative glomerulonephritis 5.0
Henoch-Schonlein purpura 5.0
systemic lupus erythematosus 4.0
other proliferative glomerulonephritis 2.0
membranous glomerulonephritis 1.0
congenital nephrotic syndrome less than less than 1.0