reduced transfer with normal ventilation
The causes of a reduced transfer factor in the presence of normal ventilatory function include:
- interstitial lung disease
- pulmonary vascular disease
- with respect to interstitial lung disease, the classic restrictive picture is of normal or even elevated FEV1/FVC ratio. However, absolute values for both FEV1 and FVC will decrease (1)
- Aaron SD et al. How accurate is spirometry at predicting restrictive pulmonary impairment? Chest. 1999 Mar;115(3):869-73.
Last reviewed 01/2018