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Neuroblastoma

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A neuroblastoma is a tumour derived from neural crest tissue and so, is properly regarded as an APUD tumour.

The most common sites are (1):

  • 50% adrenal medulla
  • 25% abdominal sympathetic ganglia
  • 20% chest
  • 5% pelvis
  • 5% neck

Extra abdominal sites generally have a better prognosis.

There is a wide spectrum of disease and in situ tumours with spontaneous remission may occur 30 times as frequently as symptomatic tumours.

Reference:

  • Grant, W. (1994). Solid Tumours in Children. Surgery, 12:6, 121-9.

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