This site is intended for healthcare professionals

account_circleSign in
Go to /sign-in page

You can view 5 more pages without signing in

Lamellar ichthyosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • lamellar ichthyosis is inherited as an autosomal recessive with an estimated incidence of less than 1 per 300,000
  • usually it starts at birth or within the first 3 months. It begins as a generalised erythema and subsequently the skin becomes thickened and scaly. The entire cutaneous area may become scaly - including flexures, palms and soles
  • the scales are large and parchment-like. They may be verrucous especially around the joints
  • additional features in some patients include palmoplantar hyperkeratosis, ectropion and scarring alopecia
  • sweating may be abnormal and the patient hyperpyrexial. Skin infections are common
  • the genetic mutation causing lamellar ichthyosis is, at present, unknown

It may present as a "collodion baby" - premature, and with shiny skin which feels hard and rigid.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.