This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages without signing in

Propranolol in migraine

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Although the usual recommended dose of propranolol is 40 mg bd, 10 mg tds may be sufficient for migraine prophylaxis.

Beta-blockers are the treatment of choice in patients whose migraine attacks are related to stress.

Migraine with or without aura (2)

  • topiramate or propranol are the suggested first line prophylactic agents
    • for the prophylaxis of migraine, offer topiramate or propranolol after a full discussion of the benefits and risks of each option. Include in the discussion:
      • the potential benefit in reducing migraine recurrence and severity
      • the risk of fetal malformations with topiramate
      • the risk of reduced effectiveness of hormonal contraceptives with topiramate
      • the importance of effective contraception for women and girls of childbearing potential who are taking topiramate (for example, by using medroxyprogesterone acetate depot injection, an intrauterine method or combined hormonal contraception with a barrier method)
    • Follow the MHRA safety advice on antiepileptic drugs in pregnancy
    • In November 2015, this was an off-label use of topiramate in children and young people
    • People with depression and migraine could be at an increased risk of using propranolol for self-harm. Use caution when prescribing propranolol, in line with the Healthcare Safety Investigation Branch's report on the under-recognised risk of harm from propranolol

Reference:

Reference:


Related pages

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.