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Diagnosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The clinical features of aplastic anaemia are non-specific. Diagnosis is based upon:

  • peripheral blood:
    • neutrophils less than 0.5 x 10^9 per litre
    • platelets less than 20 x 10^9 per litre
    • reticulocyte count corrected for haematocrit less than 1%
  • marrow:
    • severe hypocellularity
    • moderate hypocellularity with < 30% of residual cells being haematopoietic

At least two peripheral plus one marrow criteria must be satisfied.

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