Calcium antagonists are usually employed as second line agents in the treatment of hypertension. They are as effective as other hypertensive drugs when used in appropriate doses and may be, in general, used in combination with them.
Indications for the use of dihydropyridine calcium antagonists in the treatment of hypertension (1):
Indications for the use of rate limiting calcium antagonists include (1):
Contraindications to the use of rate limiting calcium antagonists include (1):
Verapamil (or diltiazem) SHOULD NOT be combined with beta-blockade on account of it's tendency to cause heart block and impair ventricular contractility.
Reference:
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