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Dipyridamole

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Dipyridamole is an anti-platelet drug which is indicated for:

  • prevention of thromboembolism in patients with prosthetic heart valves, in combination with oral anticoagulation
  • secondary prevention of stroke and TIA, either alone or in combination with aspirin

Dipyridamole mode of action:

  • a phosphodiesterase inhibitor - it acts to prevent the conversion of cyclic AMP to inactive 5' AMP
  • cyclic AMP has the action of inhibition of release of calcium from intracellular stores in the platelet (released during platelet activation and secretion)

The summary of product characteristics should be consulted before prescribing this drug.

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