C-ANCA positive conditions

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These include: Presence of C-ANCA (1)

  • Wegener's granulomatosis usually
  • microscopic polyangiitis sometimes
  • idiopathic glomerulonephritis sometimes
  • Churg-Strauss syndrome sometimes
  • ulcerative colitis sometimes

Other positive c-ANCA test results have been reported in patients with tuberculosis, Hodgkin's lymphoma, human immunodeficiency virus infection, nasal septal perforation, monoclonal gammopathies, and drug-induced Wegener-like disease (2).


  1. Walport MJ et al .Connective tissue diseases: advances in diagnosis and management.BJHM 1993: 50: 121-31.
  2. Rao JK et al. The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener's granulomatosis. Ann Intern Med 1995;123:9 25–932

Last reviewed 01/2018