Krukenberg tumour

Last reviewed 01/2018

A Krukenberg tumour is a rare metastatic ovarian tumour arising from a mucus-secreting carcinoma of the stomach or colon as a result of lymphatic spread. Most are bilateral and the stomach is the primary site most commonly implicated.

Histologically, they are characterised by "signet ring" cells with the nucleus displaced to the edge of the cell as a result of the accumulation of a mucoid substance in the cytoplasm.