This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages without signing in

MEN-IIa

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

This is the most common variant of MEN-II and is characterised by:

  • multiple phaeochromocytomas in the adrenal medulla
  • medullary carcinoma of the thyroid
  • less commonly, parathyroid hyperplasia or adenoma

Medullary thyroid tumours are present in over 90% of cases. They are usually an early sign in MEN-IIA and commonly, are very slow growing. Mortality and morbidity may be reduced significantly by screening for serum calcitonin in combination with pentagastrin stimulation.

Phaeochromocytomas are present in about 50% of cases and are a major cause of death. They should be excluded or treated in any patient with MEN-IIA.


Related pages

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.