thymoma and hypogammaglobulinaemia

Last reviewed 01/2018

These disorders may occur together in patients over 40 years of age. The patient has a mild hypogammaglobulinaemia but usually retains some IgA production.

Chronic and recurrent infections do not usually present a problem to these patients. The main difficulties arise from autoimmune phenomena such as neutropaenia, haemolytic anaemia, and sometimes myasthenia gravis.

The thymic tumour is often found on routine chest X-ray.

Surgical removal of the tumour is ineffective.