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The following drugs increase the rate of metabolism of corticosteroids, and hence reduce their efficacy:

  • carbamazepine
  • phenytoin
  • phenobarbitone
  • rifampicin

Corticosteroids may reduce the efficacy of:

  • hypoglycaemics
  • antihypertensives

They may increase the efficacy of:

  • warfarin
  • cardiac glycosides

Last reviewed 01/2018