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Mechanisms

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Three main factors are involved in the pathogenesis to angle closure glaucoma:

  • shallow anterior chamber:
    • the lens is positioned relatively anteriorly in the eye
    • often associated with hypermetropia (longsightedness)

  • lens growth:
    • the lens thickens throughout life and so encroaches on the anterior chamber

  • pupillary dilatation:
    • pupil dilatation, whether physiological or pharma- cological may block the flow of aqueous humour
    • the iris is then pushed anteriorly and comes to lie against the trabecular network
    • aqueous reabsorption is impeded
    • this process may result in acute increase in intra- ocular pressure

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