antidepressant treatment and non-steroidal anti-inflammatory drugs (NSAIDs)

Last reviewed 01/2018

Non-steroidal anti-inflammatory drugs (NSAIDs)

NICE suggest that clinicians should:

  • not normally offer SSRIs - but if no suitable alternatives can be anti-inflammatory drugs identified, offer gastroprotective medicines (for example, proton pump (NSAIDs) inhibitors) together with the SSRI
  • consider mianserin, mirtazapine, moclobemide, reboxetine or trazodone