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Diagnosis of premature ovarian insufficiency

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Diagnosing premature ovarian insuffificiency

  • take into account the woman's clinical history (for example, previous medical or surgical treatment) and family history when diagnosing premature ovarian insufficiency

  • diagnose premature ovarian insufficiency in women aged under 40 years based on:
    • menopausal symptoms, including no or infrequent periods (taking into account whether the woman has a uterus) and
    • elevated FSH levels on 2 blood samples taken 4-6 weeks apart

  • do not diagnose premature ovarian insufficiency on the basis of a single blood test
  • do not routinely use anti-Müllerian hormone testing to diagnose premature ovarian insufficiency

If there is doubt about the diagnosis of premature ovarian insufficiency, refer the woman to a specialist with expertise in menopause or reproductive medicine

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