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This is a stage of impaired glucose regulation (Fasting plasma glucose <
7.0 mmol/l and OGTT 2-hour value >= 7.8 mmol/l but < 11.1 mmol/l).
risk of subsequent conversion to diabetes is about 4.7% per year in Caucasians
and higher in some ethnic minority groups.
- these people should be followed
up annually to reassess glucose regulation and all other cardiovascular risk factors
The incidence of impaired glucose tolerance is:
of those aged 40-65 in the UK (3)
- 11% of those aged 20-74 in the US (4)
Complications of impaired glucose tolerence include:
disease - in middle aged men with glucose intolerence have double the risk of
death from cardiovascular disease (5)
- study evidence has revealed an increased
mortality risk associated with IGT (6)
- impaired glucose tolerance was associated
with an increased mortality risk (HR 1.5, 95% CI 1.1 to 2.0)
Last reviewed 01/2018