This site is intended for healthcare professionals

2693 pages added, reviewed or updated during the last month (last updated: 13/4/2021)

2693 pages added, reviewed or updated during the last month (last updated: 13/4/2021)


Medical search

caudal regression sequence

FREE subscriptions for doctors and students... click here
You have 3 more open access pages.

The caudal regression sequence describes a particular pattern of malformation which is frequently associated with maternal diabetes in pregnancy.

The sequence includes, to a variable degree:

  • incomplete development of the sacrum and lumbar vertebrae; the extreme being sacral agenesis
  • femoral hypoplasia - reduced growth of the caudal region
  • neural tube defects, with disruption of the spinal cord distally

Clinically any of the sequelae of these may be noted, in addition to which a frequent feature is flattened buttocks.

Last reviewed 01/2018

Links: