The major histocompatibility complex antigens are involved in the presentation of previously internalised antigen to T cells. The genes of the human major histocompatibility complex are located on the short arm of chromosome 6. They are otherwise refered to as human leucocyte antigen, or HLA.
Their importance increases daily as more research is performed. Also HLA associations are often the subject for stems of a multiple choice question for professional exams. However, for the practising doctor their importance lies in:
Last reviewed 01/2018