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2499 pages added, reviewed or updated during the last month (last updated: 18/4/2021)


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cholestyramine

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Indications:

  • moderate hypercholesterolaemia with normal HDL levels
  • familial hypercholesterolaemia.

Dosage:

  • 12-24g daily in single or divided doses

Side effects include:

  • nausea
  • constipation
  • heartburn
  • flatulence
  • rashes

Contra-indications include:

  • complete biliary obstruction
  • pregnancy

Cautions:

  • folic acid supplements may be required, particularly if maximal doses are used.
  • avoid taking other medications with cholestyramine;at least 1 hour before and 4 hours after, should separate ingestion of cholestyramine from that of other drugs with other drugs taken ideally first. - malabsorption of other drugs may occur, particularly: - thyroid hormones - fat soluble vitamins - oral contraception failure may occur

Comments:

  • Cholestyramine can be mixed with food, particularly muesli or fruit juice to enhance compliance. Avoid mixing with carbonated drinks.

Last reviewed 01/2018

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