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2625 pages added, reviewed or updated during the last month (last updated: 15/4/2021)


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hormonal factors

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Glucogenesis is one response to a diminution of plasma glucose levels. The hormone changes in response to low plasma glucose include:

  • increase in glucagon:
    • increases cAMP in hepatocytes which indirectly decreases the activity of 6-phosphofructokinase and pyruvate kinase
    • reduces the tendency for glycolysis to act in the opposite direction to gluconeogenesis
  • decrease in insulin: change acts to increase cAMP, so acting in tandem with glucagon
  • increase in glucocorticoids: permissive effect on other hormones

Last reviewed 01/2018

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