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The classical cell seen on histological examination is the Reed-Sternberg cell, which is a necessary, but not a sufficient element, for the diagnosis of Hodgkin's disease. Other cells seen in diseased tissue include histiocytes, lymphocytes, plasma cells, eosinophils and fibroblasts.
Currently histologic classification for adult Hodgkin lymphoma is carried out according to the World Health Organization (WHO) modification of the Revised European-American Lymphoma (REAL) classification (WHO/REAL classification)
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Last reviewed 01/2018
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