FREE subscriptions for doctors and students... click here
You have 3 more open access pages.
Hypertriglyceridaemia is most commonly due to a secondary cause.
- secondary causes of raised TG include:
- high alcohol intake, renal disease, drugs (retinoids, cyclosporin,
some beta blockers, oestrogens, corticosteroids, protease inhibitors),
bulaemia, pregnancy and, rarely, immunoglobulin excess
- possibly the most common cause of hypertriglyceridaemia is the metabolic
syndrome (insulin resistance syndrome) and type 2 diabetes
- inherited causes of a raised triglyceride include familial combined hyperlipidaemia
and lipoprotein lipase deficiency
Raised TGs are often associated with low HDL and small dense LDL particles
which are considered to be highly atherogenic.This combination is often referred
to as the atherogenic lipid triad.
Massive hypertriglyceridaemia (fasting >11mmol/L) is associated with risk
of acute pancreatitis (1).
- (1) British Heart Foundation Factfile (June 2008). Triglycerides.
Last reviewed 03/2021